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Synthesis and Antibacterial Activities of Some O-methoxy Benzene Acetic Acid Schiff Acids(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2015年02期
Page:
69-
Research Field:
化学
Publishing date:

Info

Title:
Synthesis and Antibacterial Activities of Some O-methoxy Benzene Acetic Acid Schiff Acids
Author(s):
Ji Chun12Zhou Fengli1Si Ling1
(1.School of Chemistry and Materials Science,Nanjing Normal University,Nanjing 210097,China) (2.Changzhou Institute of Materia Medica Co Ltd,Changzhou 213000,China)
Keywords:
O-methoxy phenyl acetic acidsynthesisantimicrobial activity
PACS:
O629
DOI:
-
Abstract:
O-methoxy benzene acetic acid was used to produce benzoyl hydrazine,then eight O-methoxy benzene acetic acid schiff were obtained using hydrazide derivatives and eight substituted benzene formaldehyde as starting materials.The structures of these compounds were characterized by IR,1H NMR,MS and elemental analysis.Antibacterial activity research indicated that compounds 2b and 2h had a certain inhibitory effect on Escherichia coli,Staphylococcus aureus,Bacillus subtilis,Pseudomonas aeruginosa while 2b showed good antimicrobial properties on B.Subtilis and S.aureus.

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Last Update: 2015-06-30