|Table of Contents|

Relative Electrical Impedance Variation Based Temperature MonitoringTechnology for High Intensity Focused Ultrasound Therapy(PDF)

《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2018年02期
Page:
39-
Research Field:
·物理学·
Publishing date:

Info

Title:
Relative Electrical Impedance Variation Based Temperature MonitoringTechnology for High Intensity Focused Ultrasound Therapy
Author(s):
Ding Heping; Su Huidan; Ma Qingyu; Guo Gepu
School of Physics and Technology,Nanjing Normal University,Nanjing 210023,China
Keywords:
high intensity focused ultrasound; relative electrical impedance variation; focal conductivity distribution; temperature monitoring
PACS:
O426.2
DOI:
10.3969/j.issn.1001-4616.2018.02.008
Abstract:
High intensity focused ultrasound(HIFU)can kill the tumor cells with the acousto-thermo-coagulation effects in the focal region,and it is considered to be the noninvasive technology for therapy. Based on the principle of acoustic transmission for HIFU,a composite model of HIFU therapy and electrical impedance measurement is established. Numerical studies for the distributions of the acoustic,temperature and conductivity fields in the focal region are conducted and the relative variations of the electrical impedance of the model are also achieved. It is proved that,for a fixed acoustic power,the relative impedance variation(RIV)shows a linear relationship with the treatment time and the rate of RIV increases linearly with the increase of the acoustic power. With the experimental setup,the measurements of the electrical impedance of the model are performed during the HIFU therapy,and good agreements to the simulation results are achieved. The favorable results verify the feasibility of noninvasive temperature monitoring using the RIV and also provide a new method for efficacy detection and dose control for HIFU therapy.

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Last Update: 2018-11-06