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Affinity Interaction Between Lysozyme and Hyprocrellin A:Electron Transfer and Fluorescence Quench(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2008年02期
Page:
59-64
Research Field:
化学
Publishing date:

Info

Title:
Affinity Interaction Between Lysozyme and Hyprocrellin A:Electron Transfer and Fluorescence Quench
Author(s):
Song Kaixi1Zhou Jiahong1Wu Xiaohong3Zhou Lin1Gu Xiaotian1Wei Shaohua1Feng Yuying1Wang Xuesong2
( 1. An alysis& Tes ting Cen ter, Jiangsu Eng ineering R esearch C en ter for B io-m ed ical FunctionM aterials,N an jing Norm alUn iversity, Nan jing 210097, Ch ina)
( 2. Techn ical Inst itu te of Physics and Chem istry, C hinese A cadem y of S ciences, B eijing 100101, C h ina)
( 3. D epartm en t of Eng ineering and Technology J iangsu In stitute of Econom ic T rade T echnology, Nan j ing 210007, Ch in a)
Keywords:
hypocrellin A lyso zym e b ind ing interaction photo induced e lectron transfe r
PACS:
O641.1
DOI:
-
Abstract:
Based on the know n b ind ing interaction be tw een lysozyme and hypocrellin A, a photosensitizing drug used in photodynam ic therapy, and the fluorescence quench ing m echan ism of lyso zym e by hypocrellin A w as studied. The results ind icated that the photo induced electron transfer be tw een the tryptophan and tyro sine res idues o f lysozym e and hypocre-l lin A plays an im po rtant ro le in th is fluorescence quenching process

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Last Update: 2013-05-05