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5-(4-Bromophenyl)-1,3,4-Oxadiazole-2(3H)-Thione Synthesis and Spectroscopic Properties(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2012年04期
Page:
52-54
Research Field:
化学
Publishing date:

Info

Title:
5-(4-Bromophenyl)-1,3,4-Oxadiazole-2(3H)-Thione Synthesis and Spectroscopic Properties
Author(s):
Zhou XiJiang YuliangMa ZhenmaoWang Bingxiang
Key Laboratory of Biofunctional Materials of Jiangsu Province,Research Center of Biomedical Functional Materials Engineering of Jiangsu Province,School of Chemistry and Materials Science,Nanjing Normal University,Nanjing 210023,China
Keywords:
derivatives of oxadiazole compounds fluorescent probemetal ions
PACS:
O626.2
DOI:
-
Abstract:
5-( 4-bromophenyl) -1,3,4-oxadiazole-2 ( 3H) -thione ( compound 4) was synthesized and researched of its thermal stability. The influence of the Cu 2 + ,Zn 2 + ,Co 2 + metal on their fluorescence properties were measured,and the results showed that its fluorescence could be decreased evidently by the Copper ion,while the other metal ions showed almost no effect on it. So the compound is promising to be used as the fluorescent probes for Cu 2 + . Thermal analysis showed that the compound is comparatively stable,with a decomposition temperatures above 240℃.

References:

[1] 江玉亮,邱道骥,吴婧,等. 中氮茚衍生物对金属离子选择识别性的研究[J]. 南京师大学报: 自然科学版,2008,3 ( 31) : 68-70.
[2] Pu L. Fluorescence of organic molecules in chiral recognition[J]. Chem Rev, 2004, 104: 1 687-1 716.
[3] Martinez-Manez R,Sancenon F. Fluorogenic and chromogenic chemosensors and reagents for anions[J]. Chem Rev,2003, 103: 4 419-4 476.
[4] Wei X D,Hu Y F,Hu H W, et al. A facile one-step synthesis of aromatic indolizines by 1,3 -dipolar cycloaddition of pyriydinium and related heteroaromatic ylides with alkenes in the presence of TPCD[CoPy4 ( HCrO4 ) 2 ][J]. J Chem Soc,Perkin Trans 1, 1993, 20: 2 487-2 489.
[5] Wang B X,Zhang X C,Hu Y F, et al. Preparation of indolizine-3-carboxamides and indolizine-3-carbonitriles by 1,3 -d ipolar cycloaddition of N-( cyanomethyl) pyridinium ylides to alkens in the presence of tetrakispyridinecobatt( Ⅱ) dichromate or manganese( Ⅳ) oxide[J]. J Chem Soc,Perkin Trans 1, 1999, 11: 1 571-1 575.
[6] Kwak C K,Leeb Chi Han,Lee T S. A new series of 2,5 -bis( 4-methylphenyl) -1,3 ,4 -oxadiaz ole derivatives: their synthesis and fluorescence properties for anion sensors[J]. Tetrahedron Lett, 2007, 48: 7 788-7 792.
[7] Zheng Qingzhong,Zhang Xiaomin,Xu Ying, et al. Synthesis,biological evaluation, and molecular docking studies of 2-chloropyridine derivatives possessing 1,3 ,4 -oxadiazole moiety as potential antitumor agents[J]. Bioorganic & Medicinal Chemistry, 2010, 18: 7 836-7 841.
[8] 杜海堂. 1,2,4- 三唑类衍生物的合成与生物活性[D]. 天津: 天津大学理学院化学系, 2009.

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Last Update: 2013-03-11