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《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:

2013年01期

Page:

64-67

Research Field:

化学

Publishing date:

Info

Title:

Preparation of a New Hypocrellin A-vanadyl(VO²⁺-HA)Complex and Its Photosensitive Property Studies

Author(s):

Yang Chao¹; 2; Ma Fei³; Tang Jing¹; 2; Han Lina¹; 2; Wei Shaohua²; Zhou Lin²; Zhou Jiahong¹; 2;  Shen Jian²; Ge Xuefeng¹

(1.Analysis and Testing Center,Nanjing Normal University,Nanjing 210023,China) (2.Key Laboratory of Biofunctional Materials of Jiangsu Province,Nanjing 210023,China) (3.School of Geography Science,Nanjing Normal University,Nanjing 210023,China)

Keywords:

hypocrellin A-vanadyl complex; singlet oxgen; photodamage; CT DNA

PACS:

O657

DOI:

-

Abstract:

The interaction between hypocrellin A(HA)and vanadyl(VO²⁺)was analyzed by UV-Vis and fluorescence spectra.The experiments results showed that HA and VO²⁺ can form a stable complex in aqueous solution.The complex exhibited obvious red shift,decreased absorbance and fluorescence intensity.Also,it possessed the ability of produce singlet oxygen and photodamage CT DNA.Then,the TEM was used to obtain the grain diameter of the new complex.The particle with mid-diameter of 60 nm was clearly observed.So the synthesis of the complex can further promote the application of HA in photodynamic treatment.

References:

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Last Update: 2013-03-31