|Table of Contents|

The Influence of Bitter Adaptation in Adulthood Induced by Early Postnatal Exposure to Caffeine(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2013年01期
Page:
79-84
Research Field:
生命科学
Publishing date:

Info

Title:
The Influence of Bitter Adaptation in Adulthood Induced by Early Postnatal Exposure to Caffeine
Author(s):
Liu Sisi1Li Weili1Li Guoliang1Chen Mengling2Zhang Genhua12
(1.College of Preclinical Medicine and Biological Science,Soochow University,Suzhou 215123,China) (2.College of Biology and Food Science,Changshu Institute Technology,Changshu 215500,China)
Keywords:
caffeinemouseTBPspreferenceadaptation
PACS:
Q189
DOI:
-
Abstract:
Caffeine is a prototypic bitter stimulus and is consumed as psychoactive stimulant widely.Customarily,people present aversion to caffeine.But the taste preferences can be affected by postnatal experience.Our research indicates that chronic administration of caffeine for mice at early developmental stage may influence the adult caffeine sensory.According to the behavioral test,we observed that the avoid thresholds for caffeine had been increased.Early postnatal exposure to caffeine increases the bitter adaptation in adulthood of ICR mice.

References:

[1] Drewnowski A,Henderson S A,Barratt-Fornell A.Genetic taste markers and food preferences[J].Drug Metab Dispos,2001,29(4):535-538.
[2]Schaal B,Marlier L,Soussignan R.Human foetuses learn odours from their pregnant mother’s diet[J].Chem Senses,2000,25(6):729-737.
[3]Smriga M,Kameishi M,Torii K.Brief exposure to NaCl during early postnatal development enhances adult intake of sweet and salty compounds[J].Neuroreport,2002,13(8):2565-2569.
[4]Mennella J A,Forestell C F,Morgan L.Early milk feeding influences taste acceptance and liking during infancy[J].Am J Clin Nutr,2009,90(3):780S-788S.
[5]Sclafani A.Oral,post-oral and genetic interactions in sweet appetite[J].Physiol Behav,2006,89(4):525-530.
[6]Beauchamp G K,Mennella J A.Flavor perception in human infants:development and functional significance[J].Digestion,2011,83(1):1-6.
[7]Forestell C A,Mennella J A.Early determinants of fruit and vegetable acceptance[J].Pediatrics,2007,120(6):1247-1254.
[8]Harder D B,Maggio J C,Whitney G.Assessing gustatory detection capabilities using preference procedures[J].Chem Senses,1989,14(4):547-564.
[9]Glendinning J I,Gonzalez N A.Gustatory habituation to deterrent compounds in a grasshopper:concentration and compound specificity[J].Anim Behav,1995,50(4):915-927.
[10]陆梦,张莉,丁雪瑞,等.咖啡因对小鼠空间学习记忆及体重的影响[J].西安交通大学学报:医学版,2010,31(5):648-650.
[11]张根华.甜味偏好可塑性的味觉细胞学基础[D].杭州:浙江工商大学食品与生物工程学院,2007.
[12]Laska M,Rivas B R M,Hernandez S L T.Gustatory responsiveness to six bitter tastants in three species of nonhuman primates[J].J Chem Ecol,2009,35(5):560-571.
[13]Bachmanov A A,Li X,Reed D R,et al.Positional cloning of the mouse saccharin preference(Sac)locus[J].Chem Senses,2001,26(7):925-933.
[14]Smith P F,Smith A,Miners J.The safety aspects of dietary caffeine:report from the Expert Working Group[R].Australia:New Zealand Food Authority,2000.
[15]Keast R S J,Breslin P A S.Cross adaptation and bitterness inhibition of L-tryptophan,L-phenylalanine and urea:further support for shared peripheral physiology[J].Chem Senses,2002a,27(2):123-131.
[16]Zhao F L,Lu S G,Herness S.Dual actions of caffeine ovoltage-dependent currents and intracellular calcium in taste receptor cells[J].Am J Physiol Regul Integr Comp Physiol,2002,283(1):R115-R129.
[17]Rosenzweig S,Yao W T,Dasso M,et al.Possible novel mechanism for bitter taste mediated through cGMP[J].J Neurophysiol,1999,81(4):1661-1665.
[18]Meyerhof W,Batram C,Kuhn C,et al.The molecular receptive ranges of human TAS2R bitter taste receptors[J].Chem Senses,2010,35(2):157-170.
[19]Glendinning J I,Browm H,Capoor M,et al.A peripheral mechanism for behavioral adaptation to specific“bitter”taste stimuli in an insect[J].J Neurosci,2001,21(10):3688-3696.

Memo

Memo:
-
Last Update: 2013-03-31