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Antioxidation of Boletus Aereus Polysaccharides on Alcoholic’s Injury of Mice Heart and Spleen(PDF)

《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2014年01期
Page:
133-
Research Field:
生命科学
Publishing date:

Info

Title:
Antioxidation of Boletus Aereus Polysaccharides on Alcoholic’s Injury of Mice Heart and Spleen
Author(s):
Zhao Yunxia1; Tao Mingxuan1; Guo Yongyue1; Xing Jia1; Chen Guangyu2; Gong Lianxia1
(1.Ginling College,Nanjing Normal University,Nanjing 210097,China) (2.School of Life Sciences,Nanjing Normal University,Nanjing 210023,China)
Keywords:
Boletus aereus polysaccharides; heart; spleen; alcohol; antioxidation
PACS:
TS201.4
DOI:
-
Abstract:
The antioxidation of refined polysaccharides from Boletus aereus(RPBA)on acute alcoholic hepatic injury of heart and spleen in mice were investigated.The mice were randomly divided into blank control group,alcoholic model control group and RPBA groups((200,400)mg/kg bw).All mice were administered for 30 d prior to the administration with dose of 50% alcohol(12 mL/kg bw)except blank control group.12 h after alcohol treament,all mice were dislocation death to assay activities of antioxidant capabilities in heart and spleen.The contents of MDA in heart and spleen revealed an obvious decrease in the RPBA treament groups when comparing to the model group,while the activity of SOD in the heart and spleen exhibited an obvious increase.Conclusions:RPBA can protect heart and spleen from injury induced by alcohol in mice.

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Last Update: 2014-03-30