|Table of Contents|

Magnetoacoustic Harmonic Imaging Based on Magnetic Nanoparticles(PDF)

《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2022年02期
Page:
1-8
Research Field:
·物理学·
Publishing date:

Info

Title:
Magnetoacoustic Harmonic Imaging Based on Magnetic Nanoparticles
Author(s):
Huang Yang1; Cao Ruijie1; Guo Gepu1; Ma Qingyu1; Guo Yuqing2; 1; Wang Jun2
(1.School of Computer and Electronic Information/School of Artificial Intelligence,Nanjing Normal University,Nanjing 210023,China)(2.Jiangsu Nengjian Electromechanical Industrial Co.,Ltd,Taizhou 225327,China)
Keywords:
magnetoacoustic harmonic imaging; magnetic nanoparticles(MNP); conical core; toroidal permalloy
PACS:
O441.3
DOI:
10.3969/j.issn.1001-4616.2022.02.001
Abstract:
Due to the advantages of the good magnetic response,biocompatibility and biodegradability,magnetic nanoparticles(MNPs)have been widely used in early tumor diagnoses and treatments. In this paper,an imaging method based on the magnetoacoustic harmonic response of MNPs is studied by introducing the convergence effect of a conical iron cone. Firstly,the electromagnetic excitation model with a conical core is constructed to generate a focused effective magnetic field of high magnetic field intensity and its gradient. Based on the theories of the magnetic moment,mechanical vibration and acoustic radiation of MNPs,the magnetoacoustic harmonic pressure is analyzed and derived. Then,by considering the possible phenomena of a non-ideal cone tip,the influence of the flat top on the size of the effective magnetic volume,acoustic pressure and penetration depth is studied. The favorable results show that the non-ideal cone-tip model can be used to increase the pressure of the magnetoacoustic harmonic response with a deeper penetration,while leading to a decreased imaging accuracy to a certain extent. Finally,by introducing the magnetic shielding effect of a toroidal permalloy,the spatial resolution and the contrast of the magnetoacoustic harmonic imaging are further improved,exhibiting prosperous application potentials in the superficial imaging for biological tissues.

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