|Table of Contents|

Association between Taste Sensitivity and Conlonic Diseases(PDF)

《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2017年01期
Page:
99-
Research Field:
·地理学·
Publishing date:

Info

Title:
Association between Taste Sensitivity and Conlonic Diseases
Author(s):
Chen Mengling1; Zhu Sheng2; Zhu Xi1; Zhu Wenjie1; Ju Yurui1; Zhou Xinyi1; Zhang Genhua1
(1.College of Biology and Food Engineering,Changshu Institute of Technology,Changshu 215500,China)(2.Changshu Fifth People’s Hospital,Changshu 215500,China)
Keywords:
taste; 6-n-Propylthiouracil(PROP); colon; polyps; inflammation
PACS:
Q189
DOI:
10.3969/j.issn.1001-4616.2017.01.015
Abstract:
People ready to undergo colonoscopy were recruited volenteer as subjects from several major hospitals in Changshu city. Dip-coating method was used to detect the sweet and bitter taste thresholds. The relationship between taste sensitivity and colonic diseases was discussed based on the taste tests,colonoscopy reporting and diet questionnaire. The results showed that sweet,bitter sensitivity were decreased with age. When all subjects were analyzed,the bitterness threshold of colitis and polyp groups was significantly higher than normal group,but the sweetness threshold had no significance; however,the age of colitis and polyp groups was significantly greater than the normal group. Further analysis on the age of 45～64 years(no age difference among the three groups)showed that,sweetness threshold in colitis or polyps group was significantly lower than the normal group,while the bitterness threshold did not change. It suggests that people with high sweet sensitivity,less dietary fiber intake,have higher the risk of colon disease. In addition,the sweetness threshold test has great value for the early diagnosis and treatment of colitis or colon polyps,colon cancer prevention and the protection of human health.

References:

[1] BASSON M D,BARTOSHUK L M,DICHELLO S Z,et al. Association between 6-n-propylthiouracil(PROP)bitterness and colonic neoplasms[J]. Dig Dis Sci,2005,50(3):483-489.
[2]TEPPER B J,WHITE E A,KOELLIKER Y,et al. Genetic variation in taste sensitivity to 6-n-propylthiouracil and its relationship to taste perception and food selection[J]. Ann N Y Acad Sci,2009(1 170):126-139.
[3]YANG W G,CHEN C B,WANG Z X,et al. A case-control study on the relationship between salt intake and salty taste and risk of gastric cancer[J]. World J Gastroenterol,2011,17(15):2 049-2 053.
[4]ZHONG C,LI K N,BI J W,et al. Sodium intake,salt taste and gastric cancer risk according to Helicobacter pylori infection,smoking,histological type and tumor site in China[J]. Asian Pac J Cancer Prev,2012,13(6):2 481-2 484.
[5]ZHANG Z,ZHANG X. Salt taste preference,sodium intake and gastric cancer in China[J]. Asian Pac J Cancer Prev,2011,12(5):1 207-1 210.
[6]张根华. 甜味偏好可塑性的味觉细胞学基础[D]. 杭州:浙江工商大学,2007.
[7]陈德国,武华. 复合膳食纤维对溃疡性结肠炎患者肠黏膜屏障功能的影响[J]. 中国医药导报,2013,10(4):34-38.
[8]王少鑫,高歌. 饮食对溃疡性结肠炎的致病及治疗作用[J]. 国外医学:消化系疾病分册,2003,23(1):21-23.
[9]BEAUCHAMP G K,MENNELLA J A. Early flavor learning and its impact on later feeding behavior[J]. J Pediatr Gastroenterol Nutr,2009,48(Suppl 1):S25-30.
[10]BEAUCHAMP G K,MENNELLA J A. Flavor perception in human infants:development and functional significance[J]. Digestion,2011,83(Suppl 1):1-6.
[11]MENNELLA J A,FORESTELL C A,MORGAN L K,et al. Early milk feeding influences taste acceptance and liking during infancy[J]. Am J Clin Nutr,2009,90(Suppl 1):780S-788S.
[12]CHEN M L,LIU S S,ZHANG G H,et al. Effects of early intraoral acesulfame-K stimulation to mice on the adult’s sweet preference and the expression of α-gustducin in fungiform papilla[J]. Chem Senses,2013,38(5):447-455.
[13]LI W L,CHEN M L,LIU S S,et al. Sweet preference modified by early experience in mice and the related molecular modulations on the peripheral pathway[J]. J Mol Neurosci,2013,51(1):225-236.
[14]ZHANG G H,CHEN M L,LIU S S,et al. Effects of mother’s dietary exposure to acesulfame-K in pregnancy or lactation on the adult offspring’s sweet preference[J]. Chem Senses,2011,36(9):763-770.
[15]ZHANG G H,CHEN M L,LIU S S,et al. Facilitation of the development of fungiform taste buds by early intraoral acesulfame-K stimulation to mice[J]. J Neural Transm,2010,117(11):1 261-1 264.
[16]刘斯斯,李伟丽,李国梁,等. 早期咖啡因暴露对成年小鼠苦味适应的影响[J]. 南京师大学报(自然科学版),2013,36(1):79-84.
[17]李伟丽,陈梦玲,李国梁,等. 生后发育早期甜味经历影响老年甜味偏好[J]. 南京师大学报(自然科学版),2013,36(4):100-106.

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