|Table of Contents|

Optimization of Producing Lovastatin by Eurotiumcristatum with Different Materials(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2018年02期
Page:
93-
Research Field:
·生命科学·
Publishing date:

Info

Title:
Optimization of Producing Lovastatin by Eurotiumcristatum with Different Materials
Author(s):
Yin HuihuiChen YuruZhao Wenwen
School of Life Sciences,Nanjing Normal University,Jiangsu Engineering and Technology Research Centre for Microbiology Resource,Jiangsu Key Laboratory for Biodiversity and Biotechnology,Jiangsu Key Laboratory for Microbes and Functional Genomic,Nanjing 21
Keywords:
Eurotium cristatumlovastatinvitamin B2beet powerstevia rebaudiana
PACS:
Q935
DOI:
10.3969/j.issn.1001-4616.2018.02.017
Abstract:
In this work,it is studied on the production of lovastatin by Eurotium cristatum from beet powder,beet pulp,stvia rebaudiana,glycyrrhiza residue and wheat bran as raw materials,and the effects of these materials and different factors on the yield of lovastatin were investigated. Eurotium cristatum which cultivated by beet powder had the highest lovastatin level(95 mg/kg). Vitamin B2(with a addition of 0.15%)could make the production of lovastatin significantly raise 41%(134 mg/kg)compared with no precursors. Choose 4 factors to conduct orthogonal test,the results showed the influence order of all factors are,precursors concentration(A)>inoculum concentration(D)>fermentation time(C)>fermentation temperature(B). The optimum extraction technology is A2B3C1D2,and the production of lovastatin could reach 146.4 mg/kg.

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Last Update: 2018-11-06