[1]王竹影,姜文凯,陈龙,等.中、高强度不同模式低氧训练对大鼠白细胞及其分类计数的影响[J].南京师大学报(自然科学版),2011,34(04):142-147.
Wang Zhuying,Jiang Wenkai,Chen Long,et al.The Effect of Moderate and Heavy Intensity Hypoxic Training of Different Models on the Counting of White Blood Cells and Its Classification[J].Journal of Nanjing Normal University(Natural Science Edition),2011,34(04):142-147.
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中、高强度不同模式低氧训练对大鼠白细胞及其分类计数的影响(
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《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]
- 卷:
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第34卷
- 期数:
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2011年04期
- 页码:
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142-147
- 栏目:
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体育学
- 出版日期:
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2011-12-20
文章信息/Info
- Title:
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The Effect of Moderate and Heavy Intensity Hypoxic Training of Different Models on the Counting of White Blood Cells and Its Classification
- 作者:
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王竹影1; 姜文凯2; 陈龙3; 孙福成4
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( 1. 南京师范大学体育科学学院,江苏南京210046) ( 2. 江苏省体育科学研究所,江苏南京210014) ( 3. 南京师范大学生命科学学院,江苏南京210046) ( 4. 南京农业大学体育部,江苏南京210014)
- Author(s):
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Wang Zhuying1; Jiang Wenkai2; Chen Long3; Sun Fucheng4
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1.School of Physical Education,Nanjing Normal University,Nanjing 210046,China
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- 关键词:
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训练强度; 常氧训练; 高住高练; 高住低练; 白细胞免疫
- Keywords:
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training intensity; training in normal oxygen environment; HiHi HiLo; immune function of WBC
- 分类号:
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R87
- 摘要:
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目的:研究不同强度、不同方式低氧训练后白细胞及其分类计数的变化,探讨低氧环境和训练强度对机体免疫机能的影响.方法:200只大鼠按照氧环境(常氧、高住低练、高住高练)和训练强度(无训练、中强度、高强度)随机形成9种组合,5~6周中,高强度训练后于安静状态和定量运动后即刻取样,共分15小组.Advia 120Hematology System进行白细胞及其分类计数测定.结果:5~6周HiLo中,高强度训练后基础状态下表现为低WBC血症和中性粒显著上调,而且HiLo高训组在高强度定量运动后的WBC显著低于常氧和
- Abstract:
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Objective: WBC and its classification of rats after hypoxic training of different intensity were studied to investigate the effects of different hypoxic environments and different training intensity on the immunity function of body. Methods: 200 rats were randomly divided into 9 combinations according to the oxygen concentration ( normal O2 ,living high and training low( HiLo) ,living high and training high( HiHi) ) and the training intensity ( no training,moderate intensity training( MT) and heavy intensity training( HT) ) and 15 groups including quiet and exercise states. The period of training was 5 wks ( MT) and 6 wks ( HT) ,respectively. WBC and its classification were measured by Advia 120 Hematology System. Results: 5 wks ~ 6 wks of MT and HT of HiLo led to not only the up-regulation of Neut and the downregulation of WBC in basic state,but also the WBC in HT of HiLo being significantly lower than that in HT of normal oxygen and HiHi after high intensity regular exercise. 5 wks ~ 6 wks of MT and HT in normal oxygen and HiHi did not show obvious adverse effects on the WBC and its classification,and the group of MT in HiHi even showed economizes on WBC immune function after the moderate intensity of regular exercise. The WBC decreased significantly after moderate intensity regular exercise in various oxygen environments,but it was not decreased after high intensity of regular exercise, suggesting that the phenomenon of the impression in immune system exist after moderate intensity and large amount of exercise immediately. Conclusion: HiLo is harmful to the WBC immune function,especially for the HT in HiLo. Hi- Hi did not show obvious adverse effects on WBC,and the group of MT in HiHi even show economize on WBC immune function after the moderate intensity exercise.
参考文献/References:
[1] Caldwell C C,Kojima H,Lukashev D,et al. Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effectors functions[J]. J Immunol,2001, 167( 11) : 6 140-6 149.
[2] 黄庆愿,张国斌,曾利飞,等. 急性低氧和腺苷对大鼠脾脏T 淋巴细胞增殖的影响[J]. 中国应用生理学杂志, 2004, 20 ( 3) : 214-216.
[3] Fischetti F,Fabris B,Zacearia M,et al. Effects of prolonged high-altitude exposure on peripheral adrenergic receptor in young healthy volunteers[J]. Eur J Appl Physiol,2000, 82( 5) : 439-445.
[4] Knoferl M W,Jarrar D,Schwacha M G,et al. Severe hypoxemia in the absence of blood loss causes a gender dimorphic immune response[J]. Am J Physiol Cell Physiol, 2000, 279( 6) : 2 004-2 010.
[5] Pedersen B K,Steensberg A. Exercise and hypoxia: effects on leukocytes and interleukin-6 shared mechanisms[J]. Med Sci Sports Exerc, 2002, 34( 12) : 2 004-2 013.
[6] Pyne D V,McDonald W A,Morton D S,et al. Inhibition of interferon,cytokine and lymphocyte proliferate responses in elite swimmers with altitude exposure[J]. J Interferon Cytokine Res,2000, 20( 4) : 411-418.
[7] 常芸,何子红,王莱芮,等. 高原训练对国家短道速滑运动员细胞免疫功能的影响[J]. 体育科学, 2002, 22( 1) : 86-89.
[8] Niess A M,Fehrenbach E,Strobel G. Evaluation of stress responses to interval training at low and moderate altitudes [J]. Med Sci Sports Exerc, 2003, 35( 2) : 263-269.
[9] 张缨. 4 周高住低练对外周血白细胞计数的影响[J]. 北京体育大学学报, 2004, 27( 9) : 1 213-1 218.
[10] Baum M,Klopping-Menke K,Muller-Steinhardt M,et al. Increased concentrations of interleukin-1-beta in whole blood cultures supernatants after 12 weeks of moderate endurance exercise[J]. Eur J Appl Physiol Occup Physiol, 1999, 79( 6) : 500- 503.
[11] Lehmann M J,Lomes W,Opitz-Gress A,et al. Training and overtraining: an overview and experimental results in endurance sports[J]. J Sports Exerc, 1997, 37( 1) : 7-17.
[12] Hooper S L,Mackinnon L T,Howard A. Physiological and psychometric variables for monitoring recovery during tapering for major competition[J]. Med and Sci Sports Exerc, 1999, 31( 8) : 1 205-1 210.
[13] Pedesen B K,Bruunsgaard H,Klokker M,et al. Exercise-induce immunomodulation-possible roles of neuroendocrine and metabolic factors[J]. Int J Sports Med, 1997, 18( 1) : 2-7.
[14] Rincon E O,Marchena J M,Garcia J J,et al. Phagocytie function in cyclists: correlation with catecholamines and cortisol [J]. J Appl Physiol, 2001, 91( 3) : 1 067-1 072.
[15] Reichardt H M,Kaestner K H,Tuckermann J,et al. DNA binding of the glucocorticoid receptor is not essential for survival [J]. Cell, 1998, 93( 4) : 531-541.
[16] 周瑞祥,林建银. 胸腺T 细胞分化发育的神经内分泌调控[J]. 解剖科学进展,2006, 12( 2) : 168-174.
[17] Pedersen B K,Laurie H G. Exercise and the immune system: regulation,integration and adaptation[J]. Physiol Rev, 2000, 80( 3) : 1 055-1 081.
[18] Isowa T,Ohira H,Murashima S. Reactivity of immune,endocrine and cardiovascular parameters to active and passive acute stress[J]. Biol Psychol, 2004, 65( 2) : 101-120.
备注/Memo
- 备注/Memo:
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基金项目: 江苏省基础研究计划( 自然科学基金) ( BK2009405) .通讯联系人: 王竹影,博士,教授,研究方向: 运动与健康促进. E-mail: wangzhuying2002@ yahoo. com. Cn
更新日期/Last Update:
2013-03-21