[1]张晓兵,龚毅君,苏 莉,等.基于罗丹明螺环衍生物的荧光探针研究进展[J].南京师大学报(自然科学版),2015,38(02):1.
　Zhang Xiaobing,Gong Yijun,Su Li,et al.Fluorescent Probes Based on Rhodamine Spirocyclic Derivatives[J].Journal of Nanjing Normal University(Natural Science Edition),2015,38(02):1.
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基于罗丹明螺环衍生物的荧光探针研究进展()
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《南京师大学报》（自然科学版）[ISSN:1001-4616/CN:32-1239/N]

卷:
第38卷
期数:
2015年02期
页码:
1
栏目:
特约稿
出版日期:
2015-06-30

文章信息/Info

Title:
Fluorescent Probes Based on Rhodamine Spirocyclic Derivatives
作者:
张晓兵1; 龚毅君2; 苏 莉2; 毛国江2
(1.分子科学与生物医学实验室,化学生物传感与计量学国家重点实验室,湖南大学化学化工学院,湖南 长沙 410082) (2.河南师范大学化学化工学院,河南 新乡 453007)
Author(s):
Zhang Xiaobing1; Gong Yijun2; Su Li2; Mao Guojiang2
(1.Molecular Science and Biomedicine Laboratory,State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering,Hunan University,Changsha 410082,China) (2.School of Chemistry and Chemical Engineering,Henan Normal University,Xinxiang 453007,China)
关键词:
罗丹明; 荧光探针; 螺环衍生物; 反应型探针; 配位型探针
Keywords:
rhodamine; fluorescent probe; spirocyclic derivative; coordination-type probe; reaction-type probe
分类号:
O657.3
文献标志码:
A
摘要:
罗丹明螺环衍生物在目标物的诱导下可发生螺环的开关并导致荧光信号的改变,利用该原理构建荧光探针成为传感领域的研究热点. 在过去的10多年中,大量文献报道了基于罗丹明螺环衍生物的荧光探针用于多种目标物的检测,如金属离子(Cu2+、Hg2+、Fe3+、Zn2+、Cr3+、Ag+、Au+、Pb2+和Pd2+)、阴离子(OCl-、CN-和P2O4-7)、活性氧簇/活性氮簇、硫醇类化合物、pH值以及温度等等. 本综述将分类探讨已报道的罗丹明荧光探针的响应机理,并介绍其在生物分析方面的初步应用研究.
Abstract:
Spirocyclic derivatives of rhodamine dyes have been proven to be useful fluorescence sensing platforms,since the target-triggered ring-opening process of the spirocycle could result in turn-on fluorescence response. In the past ten years,a large number of rhodamine spirocyclic derivative-based fluorescent probes have been developed,with the analytic targets including various metal ions(Cu2+,Hg2+,Fe3+,Zn2+,Cr3+,Ag+,Au+,Pb2+,and Pd2+),anions(OCl-,CN-,and P2O4-7),reactive oxygen/nitrogen species,thiols,pH values,temperatures,etc. This review will introduce the response mechanisms of previously reported rhodamine spirocyclic probes,as well as their bioanalysis applications.

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备注/Memo

备注/Memo:
收稿日期:2014-09-16.
基金项目:国家自然科学基金(21325520、J1210040、21177036)、湖南省自然科学基金(11JJ1002).
通讯联系人:张晓兵,教授,博导,杰出青年基金获得者,研究方向:有机小分子荧光探针. E-mail:xbzhang@hnu.edu.cn
更新日期/Last Update: 2015-06-30