[1]刘倩,戴志晖.固定化蛋白质在沸石和介孔分子筛上的直接电子转移及生物传感[J].南京师大学报(自然科学版),2011,34(02):54-59.
 Liu Qian,Dai Zhihui.Direct Electron Transfer of Proteins Immobilized on Zeolite/Mesoporous Molecular Sieves and Their Biosensing Applications[J].Journal of Nanjing Normal University(Natural Science Edition),2011,34(02):54-59.
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固定化蛋白质在沸石和介孔分子筛上的直接电子转移及生物传感()
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《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

卷:
第34卷
期数:
2011年02期
页码:
54-59
栏目:
化学
出版日期:
2011-06-20

文章信息/Info

Title:
Direct Electron Transfer of Proteins Immobilized on Zeolite/Mesoporous Molecular Sieves and Their Biosensing Applications
作者:
刘倩 戴志晖
南京师范大学化学与材料科学学院, 江苏南京210046
Author(s):
Liu QianDai Zhihui
School of Chemistry and Environmental Science,Nanjing Normal University,Nanjing 210046,China
关键词:
蛋白质 沸石 介孔分子筛 直接电子转移 生物传感
Keywords:
pro te in zeo lite m esoporous sieves direct e lectron transfer biosensor
分类号:
O629.73
摘要:
氧化还原蛋白质和电极之间的直接电子转移在理论和实验上都具有重要的意义.通过对蛋白质和电极的修饰能够促进它们之间的直接电子转移.蛋白质与电极表面直接接触易导致蛋白质变性,在电极表面固定沸石或介孔分子筛可为氧化还原蛋白质提供一个类似于天然状态的微环境,通过分子筛的传输通道加速直接电子转移.本文主要介绍在沸石和介孔分子筛上固定化的蛋白质的电子转移和生物传感,并重点评述这些方面的研究进展、遇到的挑战及发展趋势.
Abstract:
Direct e lectron transfe r between redox proteins and electrodes is o f practical and theoretical interest and can be improved by electrode o r pro te in m odification. The d irect contact o f prote in w ith e lectrode surfaces can lead to a sign ifican t change o f the prote in structure and /or function. Immob ilized m icroporous and m esopo rous m olecular sieves on e lectrode sur faces prov ides am icroenv ironm ent sim ilar to that o f the redox prote in in native system s and g ives the prote in m olecu lesm o re freedom in or ientation, thus fac ilitating the d irect e lec tron transfer through the conduc ting tunnels o fm olecu la r s ieves. Th is brief rev iew focuses on the m icroporous and m esoporous m o lecu lar sieves used for pro te in imm ob-i lization, e lectron transfer and b iosensing, w ith emphasis on recent adv ances, cha llenges and trends

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金( 20875046)、教育部优秀人才支持计划(NCET - 09- 0159 ) 通讯联系人: 戴志晖, 博士, 教授, 博士生导师, 研究方向: 生物电分析化学. E-m ail:daizh ihuii@njnu. edu. cn
更新日期/Last Update: 2011-06-15