[1]高 阳,李衍方,方正杰,等.噁二唑类化合物改性聚砜材料的制备及其抑菌活性[J].南京师范大学学报(自然科学版),2016,39(04):0.[doi:10.3969/j.issn.1001-4616.2016.04.023]
　Gao Yang,Li Yanfang,Fang Zhengjie,et al.Preparation and Antibacterial Activities of PolysulfoneMaterial Modified by Oxadiazoles[J].Journal of Nanjing Normal University(Natural Science Edition),2016,39(04):0.[doi:10.3969/j.issn.1001-4616.2016.04.023]
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噁二唑类化合物改性聚砜材料的制备及其抑菌活性()
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《南京师范大学学报》（自然科学版）[ISSN:1001-4616/CN:32-1239/N]

卷:
第39卷
期数:
2016年04期
页码:
0
栏目:
·化学·
出版日期:
2016-12-30

文章信息/Info

Title:
Preparation and Antibacterial Activities of PolysulfoneMaterial Modified by Oxadiazoles
文章编号:
1001-4616(2016)04-0139-04
作者:
高 阳1; 李衍方1; 方正杰1; 丁 宁1; 刘 浩1; 王炳祥2
(1.徐州市产品质量监督检验中心,江苏 徐州 221000)(2.南京师范大学化学与材料科学学院,江苏 南京 210097)
Author(s):
Gao Yang1; Li Yanfang1; Fang Zhengjie1; Ding Ning1; Liu Hao1; Wang Bingxiang2
(1.Xuzhou Product Quality Supervision and Inspection Center,Xuzhou 221000,China)(2.School of Chemistry and Materials Science,Nanjing Normal University,Nanjing 210097,China)
关键词:
噁二唑类化合物; 聚砜; 改性; 抑菌性
Keywords:
oxadiazole derivatives; polysulfone; modify; antibacterial activity
分类号:
O621.2
DOI:
10.3969/j.issn.1001-4616.2016.04.023
文献标志码:
A
摘要:
本文设计合成了噁二唑类化合物5-(2-甲氧基苯基)-1,3,4-噁二唑-2-硫醇(4a)和5-苯基-1,3,4-噁二唑-2-硫醇(4b),分别通过1H NMR和MS对其结构进行了表征,并进一步将其用于聚砜共混改性,得到了不同比例的改性产物,研究了其对大肠杆菌、金黄色葡萄球菌、绿脓杆菌及枯草杆菌的抑菌性能. 结果表明分别经化合物4a和4b改性后的聚砜材料呈现出不同的抑菌效果. 其中,化合物4a改性的聚砜材料对大肠杆菌具有较好的抑菌作用.
Abstract:
In this paper,two oxadiazole derivatives 5-(2-methoxy-benzyl)-[1,3,4]oxadiazole-2-thiol(4a)and 5-phenyl-[1,3,4]oxadiazole-2-thiol(4b)were designed and synthesized,which were further confirmed by1H NMR and MS. The obtained compounds were used for the modification of polysulfone blend for giving the modified products. The antimicrobial properties on Escherichia coli,Staphylococcus aureus,Pseudomonas aeruginosa and Bacillus subtilis were further studied and the result showed that compound 4a and 4b exhibited different antibacterial effects. The polysulfone materials modified by compound 4a have good inhibitory effect on Escherichia coli.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2015-10-15.
基金项目:江苏省优势学科建设工程资助项目.
通讯联系人:高阳,工程师,研究方向:有机合成. E-mail:gaoyangfirst@163.com
更新日期/Last Update: 2016-12-31