[1]蒋华驰,陈 员,陈静瑜.心脏死亡供肺肺移植临床分析[J].南京师范大学学报(自然科学版),2017,40(02):92.[doi:10.3969/j.issn.1001-4616.2017.02.016]
 Jiang Huachi,Chen Yuan,Chen Jingyu.Clinical Analysis of Lung Transplantation from Donor of Cardiac Death[J].Journal of Nanjing Normal University(Natural Science Edition),2017,40(02):92.[doi:10.3969/j.issn.1001-4616.2017.02.016]
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心脏死亡供肺肺移植临床分析()
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《南京师范大学学报》(自然科学版)[ISSN:1001-4616/CN:32-1239/N]

卷:
第40卷
期数:
2017年02期
页码:
92
栏目:
·生命科学·
出版日期:
2017-06-29

文章信息/Info

Title:
Clinical Analysis of Lung Transplantation from Donor of Cardiac Death
文章编号:
1001-4616(2017)02-0092-06
作者:
蒋华驰陈 员陈静瑜
南京医科大学附属无锡市人民医院胸外科,江苏 无锡 214023
Author(s):
Jiang HuachiChen YuanChen Jingyu
Department of General Thoracic Surgery,Wuxi People’s Hospital,Nanjing Medical University,Wuxi 214023,China
关键词:
心脏死亡供肺管理肺移植
Keywords:
cardiac deathdonor managementlung transplantation
分类号:
R655
DOI:
10.3969/j.issn.1001-4616.2017.02.016
文献标志码:
A
摘要:
探讨心脏死亡供体(DCD)肺移植围手术期供肺保护策略对肺移植术后的疗效. 回顾性分析2015年1月至2015年12月无锡市人民医院肺移植中心完成的21例DCD供肺移植的临床资料,受者原发病种包括肺间质纤维化9例,慢性阻塞性肺疾病4例,支气管扩张4例,硅肺2例,肺结核毁损肺1例,特发性肺动脉高压1例. 总结分析供肺术前维护策略及受者术后早期死亡原因. 21例受者手术过程顺利,术后5例受者早期死亡(<30 d),原因包括2例肺部感染,1例原发性移植物功能丧失(PGD),1例急性排斥反应(AR),1例肺栓塞. 受者术后肺功能较术前显著改善,术后1年存活率76.1%. 心脏死亡供肺经有效维护供肺可扩展供肺数量.
Abstract:
To investigate the outcome of lung management for donors after cardiac death(DCD)during preoperative period. 21 lung transplantations from DCD donors were performed in Wuxi People’s Hospital from January 2015 to November 2015. In which there were 9 pulmonary fibrosis,4 chronic obstructive pulmonary disease,4 bronchiectasis,2 silicosis,1 pulmonary tuberculosis,1 idiopathic pulmonary arterial hypertension. We retrospectively summarized the donor protective strategies and analyzed the causes of early death of recipients. 21 lung transplants were performed successfully. In-hospital mortality(<30 d)was 5/21. Death after transplantation was due to infection(n=2),primary lung graft dysfunction function(n=1),acute rejection(n=1),pulmonary vein embolism(n=1). The 1-year survival rate after lung transplants was 76.1% and the pulmonary function was improved significantly. The application of effective management in donors of cardiac could be used to significantly increase the donor pool.

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备注/Memo

备注/Memo:
收稿日期:2016-11-12.
基金项目:南京医科大学科技发展基金面上项目(2015NJ-MU146).
通讯联系人:陈静瑜,主任医师,博士生导师,研究方向:肺移植. E-mail:chenjingyu333@sina.com
更新日期/Last Update: 2017-06-30