|Table of Contents|

Influence of Different Refining Methods on the Content of Four Active Components in Si-Ni-San(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2007年03期
Page:
75-78
Research Field:
生命科学
Publishing date:

Info

Title:
Influence of Different Refining Methods on the Content of Four Active Components in Si-Ni-San
Author(s):
Liu HaiYang XinghaoZi PengLiu FeiKuang Huifen
Pharmaceutical R&D Center,Nanjing Normal University,Nanjing 210097,China
Keywords:
sin isan a lcoho l sedim entation ultra filtration m acroporous resin abso rption sa ikosapon in a paeon iflo rin nar ing in g lycyrrh izic ac id
PACS:
R284
DOI:
-
Abstract:
The decoction o f S in isan w as refined respectively by alcoho l sedim entation, u ltrafiltra tion, and m acroporous res in abso rption. The refining effects we re com pared acco rd ing to con tent o f the active com ponents and y ield o f the dry extract. The recovery o f sa ikosapon in a ( 87.29% ) by u ltrafiltration was quite rem arkable, the recovery o f paeon iflo rin ( 85. 04% ) and naring in ( 93. 52% ) by a lcoho l sedim enta tion were the h ighest. M acroporous resin recovered most of sa ikosapon in a ( 88. 14% ) and naring in ( 85. 57% ), and it also decreased the y ield of dry extract by the largest amount, therefore enriched the active com ponen ts. To develop a sc ientific and feasible refin ing process of S i- N i- San, the content o f several kinds o f active components, rathe r than on ly one k ind, shou ld be mon itored.

References:

[ 1] 高玉祥. 四逆散治疗功能性消化不良60例[ J] . 安徽中医临床杂志, 2002, 14( 3) : 179.
[ 2] 周向阳, 王世勋, 王荣林. 四逆散为主治疗肠易激综合征120例[ J]. 国医论坛, 1999, 14( 1): 7.
[ 3] 郭际. 四逆散有效成分提取和成分分析研究[ D]. 成都: 成都中医药大学, 2003.
[ 4] 李春成. 复方四逆散活性部位分离纯化的研究[ D]. 南京: 南京师范大学, 2005.
[ 5] Zhang L, DongY, Sun Y, e t a.l Ro le o f fourm ajor com ponents in S i- N i- San, a traditiona lCh inese prescription, again stcontact sensitiv ity in m ice [ J]. J Pharm Pha rm aco ,l 2006, 58( 9): 1 257-1 264.
[ 6] 徐强. 中药成分在方剂中的作用及其研究思路[ J] . 中国天然药物, 2006, 4( 5): 327-331.
[ 7] 刘岱, 杨立新, 崔淑莲. 高效液相色谱法测定柴贯冲剂中柴胡皂甙A的含量[ J]. 中国中药杂志, 1998, 23( 2): 92-93.
[ 8] 国家药典编委会. 中国药典(一部) [M ] . 北京: 化学工业出版社, 2000: 79.
[ 9] 李秀玲, 李龙, 肖红斌. 反相高效液相色谱法测定枳实枳壳中橙皮甙和柚皮甙的含量[ J]. 色谱, 2002, 20( 6): 585-586.
[ 10] 国家药典编委会. 中国药典(一部) [M ]. 北京: 化学工业出版社, 2005: 59-60.
[ 11] 付建华, 付宇, 刘建勋. % 组分中药学&假说的构想[ J] . 中药研究与开发, 2006, 13( 1): 52-54

Memo

Memo:
-
Last Update: 2013-05-05