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《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:

2008年03期

Page:

76-80

Research Field:

化学

Publishing date:

Info

Title:

Preparation and Drug-releasing Performance Research of Polylactic Acid-cefazolin Sodium Microspheres

Author(s):

Feng Xiaojian¹; ²; Wang Wei¹; ²; Zhao Min¹

( 1. S chool of Ch em istry and Environm ental S cience, Nan jing N orm alUn ivers ity, N an jing 210097, C hina)
( 2. S tate K ey Laboratory of So lid S tateM icrostru cture, N an jing Un ivers ity, Nanj ing 210093, Ch in a)

Keywords:

double em ulsion m e thod;  drug- releasing;  poly lac tic ac id;  ce fa zolin sod ium;  m icrosphere

PACS:

R94

DOI:

-

Abstract:

The PLA-CEZ m icrosphe res w ere prepared successfu lly by the doub le emu ls ion m ethod and were character ized by scann ing electron m ic roscope ( SEM ) , differential therm al ana lys is ( DTA) and IR spec tro scopy. The resu lts demonstrated that the PLA-CEZ m icrospheres w ere spher ica l and po lylactic ac id m ing led togethe rw ith cefazo lin sod ium. The e ffects of m o lecularw e ight of PLA and m ed ium on the drug- re leasing perform ance of the PLA m icro spheres w ere a lso investiga ted.

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Memo

Memo:

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Common functions

Last Update: 2013-05-05