|Table of Contents|

The Prediction of MiRNA Based on Pairwise Constrains Dimensionality Reduction(PDF)

《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2010年04期
Page:
166-171
Research Field:
计算机科学
Publishing date:

Info

Title:
The Prediction of MiRNA Based on Pairwise Constrains Dimensionality Reduction
Author(s):
Wei Shuang; Yang Ming
School of Computer Science and Technology,Nanjing Normal University,Nanjing 210046,China
Keywords:
m iRNA;  pairw ise constra ins;  d im ensiona lity reduction;  pred ic tion
PACS:
TP181
DOI:
-
Abstract:
M icroRNAs are a class of non-coding RNA s o f sing le-stranded, endogenous, wh ich p lay an im po rtant ro le in gene regu lation. The pred iction o fM icroRNAs w ill help a lot to study and understand their b io log ica l function. At present, very littlew ork has been done for the prediction o fm icroRNA s by using pa irw ise constra ins. The re fo re, a fter adding local struc ture preserv ing strategy, a d im ensiona lity reduction a lgo rithm based on pa irw ise constrains is introduced to improve the pred ic tion o f m icroRNAs e ffectively. Experim ental results on m icroRNA and UC I da ta sets va lidate the perform ance o f the proposed algor ithm.

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Last Update: 2013-04-08