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Study on the Antioxidation and Polyphenoloxidase Inhibitory Activities of Polygonum Cuspidatum Extract(PDF)

《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2011年04期
Page:
111-115
Research Field:
生命科学
Publishing date:

Info

Title:
Study on the Antioxidation and Polyphenoloxidase Inhibitory Activities of Polygonum Cuspidatum Extract
Author(s):
Guo Rui1Liu Jihua1Yu Boyang12
1.Department of Complex Prescription of Traditional Chinese Medicine,China Pharmaceutical University,Nanjing 211198,China
Keywords:
Polygonum cuspidatum extractionanti-oxidative activityscavenging free radicalinhibiting polyphenoloxidase
PACS:
S567.239
DOI:
-
Abstract:
The antioxidative activity and the polyphenoloxidase inhibitory activity of 70% alcohol extraction of Polygonum cuspidatum Sieb. et Zucc. were investigated in this paper. Chemiluminescence method was employed to detect the free radical scavenging activity against O-· 2 ,·OH and H2O2 ,while L-DOPA was used as substrate for the determination of polyphenoloxidase inhibitory activity. The results indicated the extraction exhibited a higher free radical scavenging activity against O-· 2 ,·OH and H2O2 than VC ethylether,with an IC50 value of 0. 82 mg /mL,0. 39 mg /mL and 0. 008 9 mg / mL,respectively. Compared with arbutin,the extraction also showed a higher polyphenoloxidase inhibitory activity than arbutin,with an IC50 value of 0. 14 mg /mL,in a dose-dependent manner.

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Last Update: 2013-03-21