[1]赵云霞,陶眀煊,郭永月,等.黑牛肝菌多糖对酒精性损伤小鼠心脏及脾脏抗氧化作用的研究[J].南京师大学报(自然科学版),2014,37(01):133.
 Zhao Yunxia,Tao Mingxuan,Guo Yongyue,et al.Antioxidation of Boletus Aereus Polysaccharides on Alcoholic’s Injury of Mice Heart and Spleen[J].Journal of Nanjing Normal University(Natural Science Edition),2014,37(01):133.
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黑牛肝菌多糖对酒精性损伤小鼠心脏及脾脏抗氧化作用的研究()
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《南京师大学报(自然科学版)》[ISSN:1001-4616/CN:32-1239/N]

卷:
第37卷
期数:
2014年01期
页码:
133
栏目:
生命科学
出版日期:
2014-03-30

文章信息/Info

Title:
Antioxidation of Boletus Aereus Polysaccharides on Alcoholic’s Injury of Mice Heart and Spleen
作者:
赵云霞1陶眀煊1郭永月1邢 佳1程光宇2龚莲霞1
(1.南京师范大学金陵女子学院,江苏 南京 210097) (2.南京师范大学生命科学学院,江苏 南京 210023)
Author(s):
Zhao Yunxia1Tao Mingxuan1Guo Yongyue1Xing Jia1Chen Guangyu2Gong Lianxia1
(1.Ginling College,Nanjing Normal University,Nanjing 210097,China) (2.School of Life Sciences,Nanjing Normal University,Nanjing 210023,China)
关键词:
黑牛肝菌多糖心脏脾脏酒精抗氧化
Keywords:
Boletus aereus polysaccharidesheartspleenalcoholantioxidation
分类号:
TS201.4
文献标志码:
A
摘要:
本文旨在研究黑牛肝菌多糖(RPBA)对酒精性损伤小鼠心脏及脾脏的抗氧化保护作用.将小鼠随机分为空白对照组、模型对照组、RPBA中剂量组(200 mg/kg bw·d)和高剂量组(400 mg/kg bw·d),在给予各受试样品30 d后,各组小鼠禁食不禁水12 h,然后除空白组外其余3个组都灌以50%酒精,灌胃量12 mL/kg·bw,空白对照组灌等体积的蒸馏水.12 h后将各组动物处死,取心脏、脾脏测定各项抗氧化指标.结果发现,黑牛肝菌多糖能有效提高SOD活性,降低MDA含量.结论:黑牛肝菌多糖对急性酒精损伤小鼠的心脏和脾脏有一定的保护作用.
Abstract:
The antioxidation of refined polysaccharides from Boletus aereus(RPBA)on acute alcoholic hepatic injury of heart and spleen in mice were investigated.The mice were randomly divided into blank control group,alcoholic model control group and RPBA groups((200,400)mg/kg bw).All mice were administered for 30 d prior to the administration with dose of 50% alcohol(12 mL/kg bw)except blank control group.12 h after alcohol treament,all mice were dislocation death to assay activities of antioxidant capabilities in heart and spleen.The contents of MDA in heart and spleen revealed an obvious decrease in the RPBA treament groups when comparing to the model group,while the activity of SOD in the heart and spleen exhibited an obvious increase.Conclusions:RPBA can protect heart and spleen from injury induced by alcohol in mice.

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备注/Memo

备注/Memo:
收稿日期:2013-06-19.
基金项目:江苏省高校自然科学基础研究项目(10KJD550003).
通讯联系人:陶眀煊,副教授,研究方向:生物活性物质与保健功能因子.E-mail:45017@njnu.edu.cn
更新日期/Last Update: 2014-03-30