|Table of Contents|

Expression and Discussion of Bone Morphogenetic Protein 7 in the Rabbit Ovary(PDF)

《南京师大学报（自然科学版）》[ISSN:1001-4616/CN:32-1239/N]

Issue:
2009年04期
Page:
94-97
Research Field:
生命科学
Publishing date:

Info

Title:
Expression and Discussion of Bone Morphogenetic Protein 7 in the Rabbit Ovary
Author(s):
Li Lin; Yin Ping; Ji Jinqiang; Ding Jiatong
College of Animal Science and Technology,Yangzhou University,Yangzhou 225009,China
Keywords:
rabbit;  bone m orphogene tic pro te in7( BMP7);  ov ary;  imm unoh istochem istry
PACS:
Q492
DOI:
-
Abstract:
To discuss the ac tions of bonem o rphog enetic prote in 7 ( BMP7) in the process o f fo llicu lar deve lopm ent, lute in ization and ovu lateon, w e exam ined the localization of BMP7 prote in in the rabbit ov ary using imm unohistochem ica l m e thod. The results showed that BMP7 pro te in w as no t expressed in pr imo rdia l or prim ary fo llic les. Instead, it w as found in both oocytes o f secondary fo llic les and all ce lls of antral fo llic les. It was a lso detected in interstitia l ce lls, corpora lutea and ovarian surface epithelia l cells. These suggested tha t BMP7 did not take pa rt in the activation of a do rm ant prim ord ial follic le, but p layed a ro le in the pr im ary / secondary transition and in the fo llow ing m atura tion o f fo llic les. Besides, BM P7 w as not only the cytokine of theca inte rna ce lls but a lso tha t o f oocytes and granulosa cells, BMP7 m ight a-l so partic ipate in the regulatory activ ities o f co rpora lutea, ovulation, e tc.

References:

[ 1]  Sh im asaki S, Zachow R J, L iD, et a.l A functiona l bonem orpho-gene tic prote in system in the ova ry[ J]. ProcN atlAcad Sc iUSA, 1999, 96: 7 282-7 287.
[ 2]  Sh im asak i S, K elly R, Fum ioO, et a .l The bonem orphogenetic pro te in system in m amm alian reproduction[ J]. Endocr ineReview s, 2003, 25( 1): 72-101
[ 3]  E rickson G F, Sh im asaki S. The spatiotem po ra l express ion pattern o f the bonem orphog enetic prote in fam ily in ra t ovary cell types dur ing the estrous cyc le[ J]. Reprod B io l Endoc, 2003, 1: 9.
[ 4]  LeeW, Otsuka F, M oore R K, e t a.l The e ffect o f bone m orphogene tic pro tein-7 on fo llicu logenesis and ovu lation in the rat[ J]. B iol Reprod, 2001, 65: 994-999
[ 5]  Fateh iA N, van den Hurk R, Co lenbrande rB, et a.l Expression o f bonem o rphog enetic prote in2 ( BM P2), BMP4 and BMP recepto rs in the bov ine ovary but absence of e ffects o f BMP2 and BMP4 dur ing IVM on bov ine oocyte nuc learm aturation and
subsequent embryo deve lopm ent[ J] . Theriog enology, 2005, 63: 872-889.
[ 6]  Abir R, Ben-H a roush A, M elam ed N, et a.l Expression o f bonem orphogene tic pro te in4 and 7and their receptors IA, IB, and in hum an ov aries fo rm fe tuses and adults[ J]. 2008, 89( 5 Suppl): 1 430-1 440.
[ 7]  Jenn ifer L Juenge ,l Karen L Reade r, Adrian H B ibby, et a.l The role of bone mo rphogenetic prote ins 2, 4, 6 and 7 dur ing ovarian fo llicular deve lopm en t in sheep: contrast to rat[ J]. Reproduction, 2006, 131: 501-513.
[ 8]  E rickson G F. The ova ry: basic pr inciples and concepts[ C ] / /Felig P, Frohm an L. Endocrino logy and m etabo lism. 4th ed.New Yo rk: M cGraw H il,l 2001: 707-743.
[ 9]  T illy J L. Apoptosis and ovar ian function[ J]. Rev Reprod, 1996, 1: 162-172.
[ 10]  Yam amo to N, Chr istenson L K, M cA llister JM, et a .l Grow th differentia tion factor-9 inhib its 3’5’-adenos ine monophosphate-stimu lated stero idogenesis in hum an granulosa and theca cells[ J]. C lin Endoc rino lM e tab, 2002, 87: 2 849-2 856.
[ 11]  Silva j RV, Van D, Van T, et a.l Expression of g row th d ifferen tiation factor 9 ( GDF9 ), Bone m orphogene tic pro te in 15( BMP15), and BMP receptors in the ovar ies o f goats[ J]. M o lecu lar reproduction and deve lopm en t, 2005, 70: 11-19.

Memo

Memo:
-
Last Update: 2013-04-23